Kabal Evidence Index
Kabal Peptide Index
Peptides, ranked by evidence. Not vibes.
Mechanisms, studies, anecdotes, risks, and what to track if you are experimenting.
Evidence grade
A to D, based on human data first
Anecdote grade
How loud and consistent the real-world signal is
Risk level
Low, medium, or high, with no clinic fairy dust
What to track
The labs and outcomes that keep people honest
Research peptide database
Start with the compounds people actually search.
This is version one. The point is not to crown winners. The point is to separate evidence from campfire stories.
Healing and injury recovery
BPC-157
The injury peptide with loud anecdotes and mostly animal data.
BPC-157 is interesting for tendons, ligaments, gut injury, and inflammation. The signal is real enough to study seriously, but humans are still running miles ahead of the trial pipeline.
Human data
Thin
Anecdotes
Grade A
Track
Pain score
Healing and mobility
TB-500
The mobility peptide people stack with BPC-157.
TB-500 is usually discussed as a systemic recovery and soft-tissue peptide. The biology is plausible, but the consumer protocol culture is much more confident than the human evidence.
Human data
Limited
Anecdotes
Grade B
Track
mobility score
Fat loss and metabolic health
Semaglutide
The GLP-1 that made appetite optional.
Semaglutide has strong human evidence for weight loss and glycemic control. The real question is not whether it works. It is whether users preserve muscle, hormones, and sanity while using it.
Human data
Strong
Anecdotes
Grade A
Track
weight
Fat loss and metabolic health
Tirzepatide
The dual incretin hammer for weight loss.
Tirzepatide has very strong human data for obesity and diabetes. It is one of the rare peptide-adjacent compounds where the clinical evidence is louder than the influencer anecdotes.
Human data
Strong
Anecdotes
Grade A
Track
weight trend
Growth hormone axis and visceral fat
Tesamorelin
A GHRH analog with real human data in a narrow lane.
Tesamorelin is one of the more legitimate growth-hormone-axis peptides because it has human data and an FDA-approved indication for HIV-associated lipodystrophy. Outside that lane, confidence drops.
Human data
Moderate
Anecdotes
Grade B
Track
IGF-1
Growth hormone axis and recovery
Ipamorelin
The GH secretagogue people like because it feels cleaner.
Ipamorelin is popular for sleep, recovery, and body composition, but the consumer claims lean heavily on mechanism and anecdote. Treat it as exploratory, not proven.
Human data
Thin
Anecdotes
Grade B
Track
sleep score
Hormones and fertility signaling
Kisspeptin-10
The HPT-axis signal peptide that sounds more magical than it is.
Kisspeptin-10 is mechanistically fascinating because it sits upstream of GnRH, LH, FSH, and testosterone signaling. That does not make it a magic fertility button.
Human data
Limited
Anecdotes
Grade C
Track
LH
Growth hormone axis and recovery
CJC-1295 with DAC
The long-acting GHRH analog that keeps IGF-1 elevated.
CJC-1295 with DAC has human data showing sustained GH and IGF-1 increases. The open question is whether chronic elevation is actually what you want outside clinical research.
Human data
Moderate
Anecdotes
Grade B
Track
IGF-1
Growth hormone axis and recovery
Sermorelin
The older GHRH analog with a cleaner clinical history.
Sermorelin has a more boring profile than the flashier GH peptides, which is partly why it is interesting. Human GH stimulation data exists, but optimization claims still outrun outcomes.
Human data
Moderate
Anecdotes
Grade B
Track
IGF-1
Growth hormone secretagogues
GHRP-2
A potent GH secretagogue with more hormonal spillover than the “clean” options.
GHRP-2 can move growth hormone in humans. The tradeoff is that appetite, cortisol, and prolactin can enter the room too.
Human data
Moderate
Anecdotes
Grade B
Track
IGF-1
Growth hormone secretagogues
GHRP-6
The old-school GH secretagogue famous for hunger.
GHRP-6 is a classic research-peptide forum compound: real GH biology, loud appetite effects, and thin modern outcome data.
Human data
Limited
Anecdotes
Grade B
Track
appetite
Immune modulation
Thymosin Alpha-1
The immune peptide with actual clinical literature.
Thymosin Alpha-1 has a stronger human evidence base than many trendier peptides. The catch is that evidence is mostly immune and infectious-disease context, not vague wellness optimization.
Human data
Strong
Anecdotes
Grade B
Track
CBC with differential
Skin, hair, and tissue repair
GHK-Cu
The copper peptide with skincare fame and injectable hype.
GHK-Cu has plausible skin and wound-healing biology. Topical cosmetic use is one thing. Systemic injectable claims are a much bigger leap.
Human data
Limited
Anecdotes
Grade A
Track
skin photos
Sexual health and melanocortin signaling
Bremelanotide / PT-141
The libido peptide with FDA paperwork and side effects people underplay.
Bremelanotide is not just forum mythology. It has regulatory history for sexual desire, but nausea, blood pressure, and context matter.
Human data
Moderate
Anecdotes
Grade B
Track
blood pressure
Melanocortin signaling and tanning
Melanotan II
The tanning peptide with enough red flags to deserve its own drawer.
Melanotan II is popular because the effects are visible. That does not make it low-risk. Pigment changes, nausea, libido effects, and mole concerns are not footnotes.
Human data
Limited
Anecdotes
Grade A
Track
skin photos
Cognition, anxiety, and stress
Selank
The Russian anxiolytic peptide with calming anecdotes and thin Western replication.
Selank is interesting for anxiety and stress response, but the evidence base is not as clean as its fanbase makes it sound.
Human data
Limited
Anecdotes
Grade B
Track
anxiety score
Cognition and neuroprotection
Semax
The focus peptide with a lot of neuroprotection talk and uneven evidence.
Semax is plausible as a neuroactive peptide, but the jump from stroke-adjacent literature to everyday productivity is a canyon.
Human data
Limited
Anecdotes
Grade B
Track
focus score
Longevity and sleep-adjacent signaling
Epitalon
The longevity peptide people invoke when telomeres enter the chat.
Epitalon has interesting cell and aging-adjacent literature, but practical human longevity claims are far from proven.
Human data
Thin
Anecdotes
Grade B
Track
sleep timing
Sleep and stress response
DSIP
The sleep peptide with a name doing most of the marketing.
DSIP sounds like it should be a sleep cheat code. The evidence is much less satisfying than the acronym.
Human data
Thin
Anecdotes
Grade C
Track
sleep latency
Metabolic and mitochondrial signaling
MOTS-c
The mitochondrial peptide with exercise-mimetic ambition.
MOTS-c is one of the more interesting metabolic peptides on paper. Human intervention evidence is still early, so the hype should stay on a leash.
Human data
Limited
Anecdotes
Grade C
Track
fasting glucose
Immune and antimicrobial defense
LL-37
The antimicrobial peptide where immune biology gets complicated fast.
LL-37 is biologically real and immunologically interesting. That does not mean self-experimenting with it is straightforward or low-risk.
Human data
Limited
Anecdotes
Grade C
Track
CBC with differential
Social bonding and neuroendocrine signaling
Oxytocin
The “bonding hormone” that is messier than the nickname.
Oxytocin has legitimate human research, but social behavior is not a light switch. Context, dose, relationship dynamics, and baseline state matter.
Human data
Moderate
Anecdotes
Grade B
Track
mood
How to read this
Anecdotes are signal. Not verdicts.
The index links both scientific evidence and real-world reports because both matter. Studies tell us what survived controls. Anecdotes tell us what people are actually trying, where they get weird effects, and which outcomes are worth tracking.
What is the best peptide for injury recovery?
BPC-157 and TB-500 get the most attention for injury recovery, but the evidence is uneven. Track pain, function, training load, sleep, and bloodwork instead of relying on memory.
Which peptides have the strongest human evidence?
GLP-1 and dual incretin drugs like semaglutide and tirzepatide have strong human evidence for weight loss and metabolic outcomes. Most healing and GH-axis peptides have thinner human data.
Are peptide anecdotes useful?
Yes, but they are not proof. Anecdotes are useful for spotting patterns, side effects, and tracking targets. They should not outrank controlled studies or bloodwork.
What should I track during a peptide protocol?
Track the claimed outcome, the obvious risks, and the biomarkers the mechanism could affect. For example: pain and range of motion for BPC-157, IGF-1 and glucose for GH-axis peptides, lean mass and testosterone for GLP-1s.
