Kabal Evidence Index

Kabal Peptide Index

Peptides, ranked by evidence. Not vibes.

Mechanisms, studies, anecdotes, risks, and what to track if you are experimenting.

What people claim. What studies show. What your bloodwork should prove.

Evidence grade

A to D, based on human data first

Anecdote grade

How loud and consistent the real-world signal is

Risk level

Low, medium, or high, with no clinic fairy dust

What to track

The labs and outcomes that keep people honest

Research peptide database

Start with the compounds people actually search.

This is version one. The point is not to crown winners. The point is to separate evidence from campfire stories.

Healing and injury recovery

BPC-157

Evidence C Risk Medium

The injury peptide with loud anecdotes and mostly animal data.

BPC-157 is interesting for tendons, ligaments, gut injury, and inflammation. The signal is real enough to study seriously, but humans are still running miles ahead of the trial pipeline.

Human data

Thin

Anecdotes

Grade A

Track

Pain score

Healing and mobility

TB-500

Evidence C Risk Medium

The mobility peptide people stack with BPC-157.

TB-500 is usually discussed as a systemic recovery and soft-tissue peptide. The biology is plausible, but the consumer protocol culture is much more confident than the human evidence.

Human data

Limited

Anecdotes

Grade B

Track

mobility score

Fat loss and metabolic health

Semaglutide

Evidence A Risk Medium

The GLP-1 that made appetite optional.

Semaglutide has strong human evidence for weight loss and glycemic control. The real question is not whether it works. It is whether users preserve muscle, hormones, and sanity while using it.

Human data

Strong

Anecdotes

Grade A

Track

weight

Fat loss and metabolic health

Tirzepatide

Evidence A Risk Medium

The dual incretin hammer for weight loss.

Tirzepatide has very strong human data for obesity and diabetes. It is one of the rare peptide-adjacent compounds where the clinical evidence is louder than the influencer anecdotes.

Human data

Strong

Anecdotes

Grade A

Track

weight trend

Growth hormone axis and visceral fat

Tesamorelin

Evidence B Risk Medium

A GHRH analog with real human data in a narrow lane.

Tesamorelin is one of the more legitimate growth-hormone-axis peptides because it has human data and an FDA-approved indication for HIV-associated lipodystrophy. Outside that lane, confidence drops.

Human data

Moderate

Anecdotes

Grade B

Track

IGF-1

Growth hormone axis and recovery

Ipamorelin

Evidence D Risk Medium

The GH secretagogue people like because it feels cleaner.

Ipamorelin is popular for sleep, recovery, and body composition, but the consumer claims lean heavily on mechanism and anecdote. Treat it as exploratory, not proven.

Human data

Thin

Anecdotes

Grade B

Track

sleep score

Hormones and fertility signaling

Kisspeptin-10

Evidence C Risk Medium

The HPT-axis signal peptide that sounds more magical than it is.

Kisspeptin-10 is mechanistically fascinating because it sits upstream of GnRH, LH, FSH, and testosterone signaling. That does not make it a magic fertility button.

Human data

Limited

Anecdotes

Grade C

Track

LH

Growth hormone axis and recovery

CJC-1295 with DAC

Evidence B Risk Medium

The long-acting GHRH analog that keeps IGF-1 elevated.

CJC-1295 with DAC has human data showing sustained GH and IGF-1 increases. The open question is whether chronic elevation is actually what you want outside clinical research.

Human data

Moderate

Anecdotes

Grade B

Track

IGF-1

Growth hormone axis and recovery

Sermorelin

Evidence B Risk Low

The older GHRH analog with a cleaner clinical history.

Sermorelin has a more boring profile than the flashier GH peptides, which is partly why it is interesting. Human GH stimulation data exists, but optimization claims still outrun outcomes.

Human data

Moderate

Anecdotes

Grade B

Track

IGF-1

Growth hormone secretagogues

GHRP-2

Evidence B Risk Medium

A potent GH secretagogue with more hormonal spillover than the “clean” options.

GHRP-2 can move growth hormone in humans. The tradeoff is that appetite, cortisol, and prolactin can enter the room too.

Human data

Moderate

Anecdotes

Grade B

Track

IGF-1

Growth hormone secretagogues

GHRP-6

Evidence C Risk Medium

The old-school GH secretagogue famous for hunger.

GHRP-6 is a classic research-peptide forum compound: real GH biology, loud appetite effects, and thin modern outcome data.

Human data

Limited

Anecdotes

Grade B

Track

appetite

Immune modulation

Thymosin Alpha-1

Evidence B Risk Low

The immune peptide with actual clinical literature.

Thymosin Alpha-1 has a stronger human evidence base than many trendier peptides. The catch is that evidence is mostly immune and infectious-disease context, not vague wellness optimization.

Human data

Strong

Anecdotes

Grade B

Track

CBC with differential

Skin, hair, and tissue repair

GHK-Cu

Evidence C Risk Low

The copper peptide with skincare fame and injectable hype.

GHK-Cu has plausible skin and wound-healing biology. Topical cosmetic use is one thing. Systemic injectable claims are a much bigger leap.

Human data

Limited

Anecdotes

Grade A

Track

skin photos

Sexual health and melanocortin signaling

Bremelanotide / PT-141

Evidence B Risk Medium

The libido peptide with FDA paperwork and side effects people underplay.

Bremelanotide is not just forum mythology. It has regulatory history for sexual desire, but nausea, blood pressure, and context matter.

Human data

Moderate

Anecdotes

Grade B

Track

blood pressure

Melanocortin signaling and tanning

Melanotan II

Evidence C Risk High

The tanning peptide with enough red flags to deserve its own drawer.

Melanotan II is popular because the effects are visible. That does not make it low-risk. Pigment changes, nausea, libido effects, and mole concerns are not footnotes.

Human data

Limited

Anecdotes

Grade A

Track

skin photos

Cognition, anxiety, and stress

Selank

Evidence C Risk Low

The Russian anxiolytic peptide with calming anecdotes and thin Western replication.

Selank is interesting for anxiety and stress response, but the evidence base is not as clean as its fanbase makes it sound.

Human data

Limited

Anecdotes

Grade B

Track

anxiety score

Cognition and neuroprotection

Semax

Evidence C Risk Low

The focus peptide with a lot of neuroprotection talk and uneven evidence.

Semax is plausible as a neuroactive peptide, but the jump from stroke-adjacent literature to everyday productivity is a canyon.

Human data

Limited

Anecdotes

Grade B

Track

focus score

Longevity and sleep-adjacent signaling

Epitalon

Evidence D Risk Low

The longevity peptide people invoke when telomeres enter the chat.

Epitalon has interesting cell and aging-adjacent literature, but practical human longevity claims are far from proven.

Human data

Thin

Anecdotes

Grade B

Track

sleep timing

Sleep and stress response

DSIP

Evidence D Risk Low

The sleep peptide with a name doing most of the marketing.

DSIP sounds like it should be a sleep cheat code. The evidence is much less satisfying than the acronym.

Human data

Thin

Anecdotes

Grade C

Track

sleep latency

Metabolic and mitochondrial signaling

MOTS-c

Evidence C Risk Medium

The mitochondrial peptide with exercise-mimetic ambition.

MOTS-c is one of the more interesting metabolic peptides on paper. Human intervention evidence is still early, so the hype should stay on a leash.

Human data

Limited

Anecdotes

Grade C

Track

fasting glucose

Immune and antimicrobial defense

LL-37

Evidence C Risk Medium

The antimicrobial peptide where immune biology gets complicated fast.

LL-37 is biologically real and immunologically interesting. That does not mean self-experimenting with it is straightforward or low-risk.

Human data

Limited

Anecdotes

Grade C

Track

CBC with differential

Social bonding and neuroendocrine signaling

Oxytocin

Evidence B Risk Medium

The “bonding hormone” that is messier than the nickname.

Oxytocin has legitimate human research, but social behavior is not a light switch. Context, dose, relationship dynamics, and baseline state matter.

Human data

Moderate

Anecdotes

Grade B

Track

mood

How to read this

Anecdotes are signal. Not verdicts.

The index links both scientific evidence and real-world reports because both matter. Studies tell us what survived controls. Anecdotes tell us what people are actually trying, where they get weird effects, and which outcomes are worth tracking.

What is the best peptide for injury recovery?

BPC-157 and TB-500 get the most attention for injury recovery, but the evidence is uneven. Track pain, function, training load, sleep, and bloodwork instead of relying on memory.

Which peptides have the strongest human evidence?

GLP-1 and dual incretin drugs like semaglutide and tirzepatide have strong human evidence for weight loss and metabolic outcomes. Most healing and GH-axis peptides have thinner human data.

Are peptide anecdotes useful?

Yes, but they are not proof. Anecdotes are useful for spotting patterns, side effects, and tracking targets. They should not outrank controlled studies or bloodwork.

What should I track during a peptide protocol?

Track the claimed outcome, the obvious risks, and the biomarkers the mechanism could affect. For example: pain and range of motion for BPC-157, IGF-1 and glucose for GH-axis peptides, lean mass and testosterone for GLP-1s.